ACTOLIND^® GEL PLUS

No. Actolind products should not be mixed with another cream, ointment, or chemical substance before application.

Actolind gels and solutions have patented formulations in which the molecular balance of the PHMB and Poloxamer components, the biocompatibility index, and the pH level (5.0–7.5) have been specifically optimized. Therefore, mixing the product with another cream, ointment, or chemical substance may:

Impair its protective film-forming and moisture-retention properties.
Reduce or completely eliminate its antimicrobial efficacy.
Adversely affect tissue compatibility and cause irritation.

For this reason, Actolind products should be applied directly and alone to the wound bed. If a different cream or ointment has also been prescribed by a physician, the products should not be mixed; they should be used separately, following the sequence and time intervals recommended by the physician.

Actolind Gel Plus is not a product specifically developed for acne treatment and should not be used for the direct treatment of acne. Acne is a dermatological condition in which multiple factors may play a role, including sebaceous gland activity, follicular occlusion, hormonal factors, and microorganisms such as Cutibacterium acnes. Therefore, appropriate diagnosis and treatment should be determined by a dermatologist.

However, due to the antimicrobial activity provided by PHMB (Polyhexanide) and its properties that support cleansing of the skin surface, Actolind Gel Plus may be considered as supportive care in acne management. Particularly during the healing of acne-related wounds, it may help maintain the microbial load on the skin surface under control and help prevent the proliferation of certain bacteria.

Actolind Gel Plus may:

Help keep the skin surface clean.
Support the maintenance of microbial balance on skin areas with increased microbial characteristics.
Provide supportive care in cases where skin integrity is compromised or where irritation or small superficial lesions are present.

However, Actolind Gel Plus should not be regarded as a product that treats acne on its own or completely eliminates acne. During acne treatment, it may be used in addition to treatments recommended by a dermatologist as supportive care for skin cleansing and microbial load control.

The method and suitability of use should be evaluated based on the type of acne, skin sensitivity, and other treatments being used.

Actolind Gel Plus is a wound care gel with protective, moisturizing, and antimicrobial properties, used in the care of acute and chronic wounds, infected or non-infected wounds, and first- and second-degree burns. Thanks to the combination of Polyhexanide (PHMB) and Poloxamer in its formulation, it provides a multifaceted effect that supports wound care.

Its primary functions are:

Keeps the wound surface moist: Helps maintain the optimal moist wound environment required for healing.

Forms a protective film layer: Protects the wound surface from external factors while creating a barrier between the wound and the dressing, helping to provide protection and prevent the dressing from adhering to the wound.

Provides antimicrobial protection: Its PHMB content helps control the microbial load on the wound surface and contributes to reducing the risk of recontamination.

Supports wound care: Helps manage necrotic tissue, crusts, and biofilm formation; supports natural wound healing by maintaining granulation and epithelialization processes.

Facilitates dressing changes: By forming a protective layer between the wound and the dressing, the gel helps make dressing changes more comfortable and atraumatic.

Actolind Gel Plus can be used as part of an appropriate wound care protocol for many types of wounds, including diabetic foot ulcers, venous ulcers, pressure ulcers, surgical wounds, traumatic wounds, and first- and second-degree burns. For optimal results, it is recommended that the wound surface first be cleansed with Actolind W Solution, followed by the application of Actolind Gel Plus.

Its main active ingredients are Polyhexanide (PHMB, 0.1%) and Poloxamer.

Polyhexamethylene Biguanide (PHMB 0.1%) provides broad-spectrum antimicrobial protection, helping to control the microbial load on the wound surface. By binding to the bacterial membrane, it helps reduce the microbial load. At the same time, its high tissue compatibility supports the wound healing process.

Poloxamer 188: Due to its surfactant properties, it helps remove dirt, exudate, necrotic tissue residues, and biofilm formation from the wound surface. It also helps maintain an optimal wound healing environment by supporting moisture retention in the wound.

When applied, Actolind Gel Plus forms a thin, transparent, moisture-retaining protective gel layer on the wound surface. By helping to keep the wound moist, this layer supports the maintenance of an environment conducive to wound healing.

Thanks to the protective gel layer it forms:

It helps prevent the wound surface from drying out.
By creating a protective barrier between the wound and the dressing, it reduces the risk of the dressing adhering to the wound and makes dressing changes more comfortable.
It helps create a protective barrier against contamination from the external environment.
By helping maintain contact between the PHMB content and the wound surface, it supports the continuity of antimicrobial activity.
By maintaining an optimal moisture balance, it supports natural wound healing processes such as granulation and epithelialization.

To preserve the effectiveness of this protective layer, Actolind Gel Plus should be applied alone and in a sufficient amount to the wound bed; it should not be mixed with other creams, ointments, or chemical products. If other topical products are required, they should be applied separately, only in the sequence and at the time intervals recommended by the physician.

The pH value of Actolind Gel Plus ranges from 5.0 to 7.5. This range has been optimized to support tissue compatibility in wound care and ensure suitability for the physiological wound environment.

Due to this pH value, which is close to physiological pH, the product:

Demonstrates high compatibility with wound tissue.
Helps maintain a suitable microenvironment that supports the natural wound healing process.
Supports the efficacy and stability of its special formulation containing PHMB and Poloxamer.
Provides a biocompatible wound care environment that can be safely used on sensitive wound tissue.

The pH range of Actolind Gel Plus is one of the key characteristics of its patented formulation, specifically developed to contribute to creating optimal conditions for wound healing.

Yes. Its Biocompatibility Index (BI) is >1.

The Biocompatibility Index (BI) is a scientific parameter that indicates the balance between the antimicrobial efficacy of a product against microorganisms and its compatibility with human cells.

A BI value above 1 (>1) indicates that the product is effective against microorganisms while demonstrating high biocompatibility with human tissue cells. In other words, the product has high antimicrobial efficacy while having a low potential to damage cells.

For Actolind Gel Plus, a BI >1 supports the following advantages:

It contributes to safe use on the wound surface due to its high tissue compatibility.
While providing effective antimicrobial protection, it aims to minimize the risk of damage to healthy tissue.
It helps support natural wound healing processes such as granulation and epithelialization.
It provides a biocompatible product profile that is well tolerated in long-term wound care.

In summary, a BI >1 is an important indicator of biocompatibility, demonstrating that Actolind Gel Plus provides effective antimicrobial protection in wound care while also possessing tissue-friendly properties.

Yes. Actolind Gel Plus is a wound care product that has been evaluated for biocompatibility in accordance with the relevant medical device standards and has successfully passed the required biocompatibility tests.

The product’s biocompatibility is supported by tests conducted in accordance with the ISO 10993 biological evaluation standards. These assessments are intended to verify the product’s safe use and tissue tolerance when it comes into contact with wound tissue.

Due to the large polymeric structure of its active ingredients, there is no risk of cellular absorption or entry into the systemic circulation. Actolind Gel Plus is a wound care gel developed for topical (external) use and is not expected to be systemically absorbed or enter the bloodstream under appropriate conditions of use.

Its antimicrobial component, Polyhexanide (PHMB), is formulated to exert a local effect on the wound surface. Actolind Gel Plus forms a protective and moisturizing gel layer on the wound surface, allowing its antimicrobial activity to remain localized to the application site and is not designed to produce systemic effects.

No. Polyhexanide (PHMB), contained in Actolind Gel Plus, is a component that has been evaluated as part of safety assessments. In evaluations conducted by the CARC (Cancer Assessment Review Committee), Polyhexanide has been classified among substances considered “not likely to be carcinogenic to humans from dermal exposure.”

With regard to the short- and long-term health effects of Polyhexanide, current assessments indicate that there is no evidence demonstrating a carcinogenic, toxic, or genotoxic risk to human health.

Actolind Gel Plus has been developed for local use in wound care and, through the PHMB it contains, is intended to provide antimicrobial protection on the wound surface. The product’s biocompatibility characteristics and safety profile have been evaluated as suitable for use on wound tissue.

Therefore, when Actolind Gel Plus is used in accordance with the instructions for use, there are no scientific data indicating that it poses a carcinogenic risk, and it is a wound care product with an evaluated safety profile.

Actolind Gel Plus is a wound care gel used in acute wound care to support the normal healing process, maintain the moisture balance of the wound surface, and help control the microbial load. It can be used for various types of acute wounds, including sudden-onset traumatic wounds, surgical wounds, and burns.

The main types of acute wounds for which Actolind Gel Plus can be used include:

Surgical wounds:
It can be used for the care of postoperative incision sites, surgical incisions with or without sutures, and wound areas following surgical procedures.

Cuts (lacerations):
It can be used for the care of superficial and deep skin cuts caused by glass, knives, or sharp objects.

Abrasions:
It supports the care of abrasions in which the upper layer of the skin has been damaged as a result of falls, friction, or accidents.

Tears:
It helps support wound care for irregular tears involving the skin and subcutaneous tissues caused by trauma.

Puncture wounds:
It can be used as part of appropriate wound management in cases where skin integrity has been disrupted by nails, thorns, or similar objects.

Traumatic wounds:
It supports wound care in acute tissue injuries resulting from accidents, falls, impacts, or sports injuries.

Crush and compression injuries:
It can be used for skin and soft tissue injuries caused by impact or compression.

First- and second-degree burns:
In superficial burns caused by heat, hot liquids, steam, chemicals, or similar agents, it helps keep the wound surface moist and maintain an environment conducive to healing.

Skin graft donor and recipient sites:
It can be used as supportive care for wound areas resulting from skin transplantation procedures.

Wound areas following drainage, catheterization, or minor surgical procedures:
As part of an appropriate wound care protocol, it can help protect the wound surface.

Actolind Gel Plus forms a protective, moisture-retaining gel layer on the wound surface, helping to prevent the wound from drying out, facilitate dressing changes, and maintain an environment conducive to wound healing. Particularly in acute wounds at risk of contamination or infection, it can be used to help control the microbial load through the PHMB (Polyhexanide) it contains.

Before use, the type, depth, and healing status of the wound should be assessed. For deep or severe wounds, wounds showing signs of infection, or wounds requiring specialized medical intervention, the recommendations of a healthcare professional should be followed.

A chronic wound is a wound in which the normal wound healing process is not completed within the expected timeframe, remains stalled in one or more stages of healing (inflammation, proliferation, or remodeling), and persists for a prolonged period. In these wounds, tissue repair is delayed; factors such as circulatory impairment, pressure, diabetes, infection, recurrent trauma, or underlying systemic diseases may adversely affect the healing process.

Chronic wounds are generally considered to be wounds that persist for longer than 4–6 weeks or do not demonstrate a normal healing tendency.

The main types of chronic wounds for which it is effective include:

Diabetic foot ulcers
Pressure ulcers (decubitus ulcers / bedsores)
Venous ulcers
Arterial (ischemic) ulcers
Neuropathic wounds
Infected chronic wounds
Chronic surgical wounds
Chronic wounds resulting from trauma
Malignancy-associated wounds (tumor wounds)
Radiation-induced wounds
Chronic wounds following burns
Wounds associated with autoimmune diseases
Wounds associated with inflammatory diseases
Chronic wound areas associated with fistulas and sinuses
Peristomal skin wounds and wounds around stomas
Chronic wounds associated with osteomyelitis
Chronic skin ulcers associated with pressure
Wounds associated with vasculitis
Wounds associated with lymphedema

It can be used for many chronic wounds, including chronic open wounds and tissue loss.

Yes. Actolind Gel Plus can be used for wound care in many types of burns, whether infected or non-infected, particularly first- and second-degree thermal, scald, flame, and chemical burns. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps gently cleanse the wound surface, supports biofilm management, maintains a moist wound healing environment, and supports the wound care process. It also helps reduce dressing adherence to the wound, contributing to more comfortable dressing changes.

Note: Extensive, deep, or third-degree burns must be evaluated and treated by a healthcare professional.

Yes. Actolind Gel Plus can be used in the wound care of wounds and burns caused by electrical current, as well as radiation-induced wounds and burns. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps cleanse the wound surface, supports biofilm management, maintains a moist wound healing environment, and supports the wound care process.

Note: Since electrical burns and radiation injuries can cause severe tissue damage, these types of injuries must be evaluated by a healthcare professional and managed as part of an appropriate treatment plan.

Yes. Actolind Gel Plus can be used for the care of urinary, central venous, peripheral venous, dialysis, PEG, and other catheter insertion sites. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps cleanse the catheter insertion site, reduce biofilm and microbial load, and maintain a moist wound healing environment. Its PHMB content supports control of the existing microbial load; with regular and appropriate use, it contributes to reducing the risk of infection and helps maintain hygiene at catheter insertion sites. It also helps reduce dressing adherence to the tissue, supporting more comfortable care.

Yes. Actolind Gel Plus may be preferred for skin and wound care around stomas and fistulas. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps gently cleanse the area, reduce biofilm and microbial load, maintain a moist wound healing environment, and support skin integrity. Its PHMB content supports control of the existing microbial load; regular and appropriate use contributes to reducing the risk of infection and helps maintain hygiene around the stoma and fistula. It also helps reduce dressing adherence to the tissue, supporting more comfortable care.

Yes. Open wounds caused by ingrown toenails may become susceptible to bacterial accumulation and infection. Actolind Gel Plus helps maintain an appropriate moist healing environment by gently cleansing the wound surface. Thanks to its PHMB content, it supports control of the microbial load on the wound surface and contributes to reducing the risk of infection when used regularly in wound care. It also helps reduce dressing adherence to the wound surface, making wound care more comfortable, and supports the formation of healthy granulation tissue.

Yes. Actolind Gel Plus was used in a case of Aplasia Cutis Congenita (ACC) in a poster study presented at the 19th National and 7th International Wound Congress in 2025. In this case, conservative wound care was successfully performed using Actolind Solution and Actolind Gel without the need for surgical intervention.

According to the poster results, epithelialization at the wound margins and a reduction in wound size were observed by day 18, while by day 36, the necrotic tissue had completely disappeared and most of the wound had epithelialized. The study stated that conservative wound care with Actolind Gel Plus supported the wound healing process and that the results obtained were consistent with the literature.

Yes. Actolind Gel Plus can be used to prepare the wound bed before grafting and to support wound care after graft application. By helping to cleanse the wound surface and control biofilm and microbial load, it supports the formation of a wound bed suitable for grafting.

After graft application, it helps maintain a moist wound healing environment, reduces dressing adherence to the wound surface, and, with regular use, helps reduce the risk of infection. In this way, it supports graft preservation and effective continuation of the wound care process.

Yes. In cavitary wounds, it fills the wound bed and helps prevent pathogen colonization. In these types of wounds, where exudate and biofilm are prone to accumulate, its formulation containing Polyhexanide (PHMB) and Poloxamer helps cleanse the wound cavity and supports the control of biofilm and microbial load. By helping maintain a moist wound healing environment, it supports the development of granulation tissue and facilitates more effective wound care.

For cavitary wounds, it is recommended that the product be used in conjunction with appropriate dressing materials that adequately fill the wound cavity and in accordance with the assessment of a healthcare professional.

Before applying Actolind Gel Plus, the wound surface should be thoroughly cleansed with Actolind W Solution. The entire wound and the surrounding area should be cleansed to remove contaminants, debris, and wound residues. In deep wounds with extensive necrotic tissue, a compress soaked with Actolind W Solution should be applied for at least 10–15 minutes. The solution should not be diluted.

Once cleansing is complete, the wound bed should be completely covered with a sufficient amount of Actolind Gel Plus, followed by the application of an appropriate secondary dressing. Actolind Gel Plus helps maintain a moist environment on the wound surface and helps reduce dressing adherence to the wound bed.

Important: Before applying Actolind Gel Plus, no incompatible products such as soap, cream, oil, enzymes, or anionic surfactants should remain on the wound.

No. Actolind Gel Plus should not be rinsed off after application. A sufficient amount of Actolind Gel Plus is applied to the cleansed wound surface, followed by an appropriate dressing. The gel may remain on the wound until the next dressing change. Actolind W Solution may be used during the subsequent dressing change to remove the previous gel layer from the wound surface.

Yes. Actolind Gel Plus can be applied directly to the wound surface. Before application, it is recommended that the wound be thoroughly cleansed with Actolind W Solution, after which the wound bed should be completely covered with a sufficient amount of Actolind Gel Plus and appropriately dressed. The gel forms a protective layer on the wound surface, helping to maintain an optimal moist wound environment and reduce dressing adherence to the wound bed.

Whether the wound should be left open or covered should be determined according to the condition of the wound. Actolind Gel Plus may be applied to the cleansed wound surface and left in place. When necessary, it may be used together with an appropriate dressing or wound covering. However, whether the wound should be left open or covered should be determined by a physician or wound care specialist based on the wound type, depth, amount of exudate, anatomical location, and healing process. Actolind Gel Plus forms a protective film on the wound surface, helping to maintain a moist wound environment and reduce adherence between the dressing and the wound.

By forming a barrier between the wound and the dressing, it prevents the dressing from adhering to the wound and allows atraumatic (painless) dressing changes.

Yes. It can be used to moisten dried dressing materials that have adhered to the wound.

Yes. Actolind Gel Plus can be used in the care of acute and chronic wounds with established biofilm or at risk of biofilm formation. By covering the wound surface, it mechanically helps prevent microbial adhesion and the formation of new biofilm. Its Poloxamer content supports the removal of biofilm from the wound surface, while Polyhexanide (PHMB) contributes to controlling the microbial load on the wound surface. When used together with regular wound cleansing, it supports biofilm management and helps create an environment more conducive to wound healing.

There is no fixed dressing-change frequency for Actolind Gel Plus. The dressing-change frequency recommended by your physician or wound care specialist should be followed. The gel may remain on the wound surface until the next dressing change. Dressing-change frequency should be determined according to the type of wound, amount of exudate, condition of the wound bed, and the secondary dressing being used. At each dressing change, it is recommended that the wound surface be cleansed with Actolind W Solution and Actolind Gel Plus then reapplied. This helps maintain moisture on the wound surface and supports reduced adherence of the dressing to the wound bed.

Yes. It is compatible with all modern wound dressings, bandages, gauze dressings, and wound packing materials.

It is effective against MRSA (methicillin-resistant S. aureus), VRE (vancomycin-resistant enterococci), and resistant Acinetobacter baumannii.

Yes. Actolind Gel Plus is effective against fungi. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it exhibits antimicrobial activity against mycotic pathogens. It is particularly effective against Candida albicans.

No. There is no known mechanism of resistance to Polyhexanide. There is currently no evidence that bacteria develop resistance to the product during the use of Actolind Gel Plus.

No. The presence of blood does not eliminate the efficacy of Actolind Gel Plus. Actolind Gel Plus is developed for use in wound environments where blood and wound exudate are present and, thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps cleanse and moisturize the wound surface and control microorganisms.

Yes. Actolind Gel Plus has been dermatologically tested. The tests determined that the product is non-irritating, well tolerated, and does not cause sensitization. It is also stated to have high biocompatibility and not to inhibit granulation or epithelialization. It has been tested by Dermatest Laboratories in Germany and received an “EXCELLENT” rating.

It is compatible with mucosal tissues and does not cause discomfort or pain.

Yes. Thanks to its tissue-friendly properties, its safety in the wound and burn care of pediatric and infant patients has been demonstrated in clinical cases.

It does not cause sensitization and is well tolerated by allergic and diabetic patients.

Yes. Due to its high tissue compatibility, it is suitable for long-term wound treatment.

It is certified as a Class III medical device in accordance with the 93/42/EEC Medical Device Directive.

Actolind Gel Plus is available in 10 ml, 30 ml, 50 ml, 100 ml, and 250 ml tube sizes.

Yes. It is available in Monodose Strip packaging options of 25 × 5 ml, 10 × 5 ml, and 5 × 10 ml.

Actolind Gel Plus and Actolind Gel Plus should not be considered products with completely different compositions or intended purposes; they are related versions within the same Actolind gel product group. The Plus series is an alternative portfolio option with increased moisturizing capacity and viscosity due to the addition of an additional surfactant.

One of the key advantages of Actolind Gel Plus is its high biocompatibility with wound tissue while providing antimicrobial efficacy. Its combination of 0.1% Polyhexanide (PHMB) and Poloxamer is effective against bacteria, resistant microorganisms, and fungi without inhibiting granulation or epithelialization. This characteristic makes Actolind Gel Plus suitable for long-term use during different stages of wound healing and distinguishes it as a tissue-friendly wound care gel.

In products containing Octenidine, effects on tissue tolerance and granulation/epithelialization may vary depending on the formulation and concentration used. Therefore, the advantage of Actolind Gel Plus lies not only in its antimicrobial efficacy but also in its tissue-friendly properties that support wound healing.

Yes. It can be safely used in cyclic applications in combination with NPWT to promote the formation of healthy granulation tissue.

No. It is not a scar cream; it is a medical gel designed to support the infection-free closure of open wounds in a moist environment.

No. It is an open-wound care product classified as a Class III medical device and is not intended for aesthetic or cosmetic skincare purposes.

Actolind Gel Plus may help reduce overall treatment costs by contributing to more effective and efficient wound care management. In wound care, costs are determined not only by the product used, but also by recurring dressing changes, healthcare personnel time, additional consumable materials, infection management, and prolonged treatment duration.

Effective wound cleansing, biofilm management, maintenance of a moist wound environment, and sustained antimicrobial support with Actolind Gel Plus and Solution contribute to greater efficiency in the wound care process and more effective use of healthcare resources.

Yes. Actolind Gel Plus can be used in the care of diabetic foot wounds. Since the risk of infection and biofilm formation in diabetic wounds can delay wound healing, regular wound cleansing and appropriate wound care are of great importance. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, Actolind Gel Plus supports the control of microbial load and biofilm on the wound surface while helping to maintain a moist wound healing environment.

This approach was also demonstrated in a case study on diabetic foot trauma presented at the 18th National and 6th International Wound Congress in 2024. In the study, the wound bed was prepared using Actolind W Solution and Actolind Gel Plus, followed by successful graft application and wound healing.

Yes. Actolind Gel Plus can be used in the care of pressure ulcers. Regular wound cleansing, control of biofilm formation, and maintenance of a moist wound healing environment are key components of the healing process in pressure ulcers. Actolind Gel Plus helps cleanse the wound surface and contributes to maintaining an appropriate wound environment that supports the development of granulation tissue.

Particularly in chronic wound care, when used together with regular dressing applications, it helps support effective management of the wound care process.

Yes. Actolind Gel Plus can be used in the wound care of venous ulcers. In these chronic wounds caused by venous insufficiency, prolonged exudate and biofilm formation may adversely affect the healing process. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, Actolind Gel Plus helps cleanse the wound surface and control the microbial load and biofilm.

It also helps maintain a moist wound healing environment, thereby supporting the granulation and epithelialization processes. Treatment of venous ulcers should be carried out in conjunction with compression therapy and other approaches planned by the physician.

Yes. Actolind Gel Plus can be used for appropriate wound care of arterial ulcers. Although correcting impaired arterial circulation is the primary treatment for these wounds, keeping the wound surface clean and controlling the risk of infection are also important. Actolind Gel Plus helps maintain a moist wound healing environment and control the microbial load on the wound surface while supporting wound care. Treatment of arterial ulcers must be planned by a vascular surgeon or other relevant specialist.

Yes. Actolind Gel Plus can be used in the care of surgical wounds. Following surgical procedures, it is important to keep the wound surface clean, maintain an appropriate moisture balance, and manage the risk of infection in terms of the healing process. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, Actolind Gel Plus supports wound care, helps control the microbial load, and reduces dressing adherence to the wound surface, contributing to more comfortable dressing changes.

Yes. Actolind Gel Plus can be used in the care of acute wounds resulting from traffic accidents, falls, crush injuries, and similar trauma. In traumatic wounds, foreign material, tissue debris, and microbial contamination may adversely affect wound healing. Actolind Gel Plus helps cleanse the wound surface, maintain a moist wound healing environment, and control biofilm formation.

This approach was also demonstrated in a case study involving diabetic foot trauma presented at the 18th National and 6th International Wound Congress in 2024; the wound was prepared using Actolind W Solution and Actolind Gel Plus, followed by successful graft application.

Yes. After debridement, keeping the wound bed clean and controlling the reformation of biofilm are important for the continuation of wound healing. Actolind Gel Plus helps maintain a moist wound healing environment after debridement, supports microbial load control, and helps create an appropriate wound environment for the development of granulation tissue. It also reduces dressing adherence to the wound bed, contributing to less traumatic dressing changes.

Yes. Actolind Gel Plus can be used as an important part of wound bed preparation. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, it helps cleanse the wound surface and control biofilm and microbial load. In this way, it contributes to creating a wound environment that supports the development of granulation tissue and is suitable for subsequent wound care procedures.

This approach was also used in a case study presented at the 18th National and 6th International Wound Congress in 2024; after the wound bed was prepared using Actolind products, a successful skin graft was performed.

Yes. Healthy granulation tissue is one of the essential stages of wound healing. Actolind Gel Plus helps cleanse the wound surface and control biofilm and microbial load while supporting the maintenance of a moist wound healing environment. In this way, it contributes to creating appropriate wound conditions for the development of granulation tissue and supports the wound healing process.

Yes. Actolind Gel Plus can be used in the care of wounds containing necrotic tissue. Necrotic tissue may facilitate biofilm formation and delay wound healing. Actolind Gel Plus helps cleanse the wound surface and supports biofilm management, thereby contributing to the preparation of the wound bed for healing. When necessary, it can be used in conjunction with surgical, mechanical, or autolytic debridement methods.

Yes. By helping maintain the moisture balance on the wound surface, Actolind Gel Plus creates an appropriate healing environment that supports the epithelialization process. When used in conjunction with regular wound care, it helps keep the wound surface clean and supports the physiological progression of wound healing.

This was also observed in an Aplasia Cutis Congenita case poster presented at the 19th National and 7th International Wound Congress in 2025; during follow-up, epithelialization was reported to have begun at the wound margins, with most of the wound becoming epithelialized in the following days.

Yes. Actolind Gel Plus can be used in the care of infected wounds or wounds at risk of infection. Its Polyhexanide (PHMB) content supports control of the microbial load on the wound surface, while Poloxamer helps remove biofilm and wound debris. When used in conjunction with regular wound care, it contributes to reducing the risk of infection and creates an environment more conducive to wound healing. In cases with advanced signs of infection, appropriate medical treatment should be planned by a healthcare professional.

Yes. Actolind Gel Plus can be used in the care of tunneled wounds (wounds with sinus tracts). Regular wound cleansing is particularly important in these types of wounds, as biofilm, exudate, and tissue debris may accumulate within the wound cavity. Thanks to its formulation containing Polyhexanide (PHMB) and Poloxamer, Actolind Gel Plus supports cleansing of the wound surface, control of the microbial load, and maintenance of a moist wound healing environment. When necessary, it should be used in conjunction with appropriate dressing protocols and according to the recommendations of a healthcare professional.

Yes. Actolind Gel Plus can be used in the care of exudative wounds. While helping to maintain an appropriate moisture balance on the wound surface, its formulation containing Polyhexanide (PHMB) and Poloxamer supports wound surface cleansing and microbial load control. It helps enhance the effectiveness of wound care when used in conjunction with secondary dressings appropriate for the amount of exudate.

Yes. Actolind Gel Plus supports the physiological wound healing process by helping to moisturize a dry wound surface. Maintaining a moist wound healing environment is one of the fundamental principles of wound care that supports cell migration and new tissue formation. Actolind Gel Plus supports the wound care process by helping maintain the moisture balance of the wound surface.

Yes. Actolind Gel Plus forms a protective gel layer on the wound surface, helping to reduce dressing adherence to the tissue. This helps reduce mechanical trauma and associated discomfort that may occur during dressing changes. It is particularly supportive in the care of sensitive tissue and chronic wounds where wound care is more comfortable when dressing adherence is minimized.

Indirectly, yes. Actolind Gel Plus keeps the wound surface moist and helps reduce dressing adherence to the wound bed, thereby helping to minimize tissue trauma that may occur during dressing changes. This can contribute to more comfortable dressing changes. However, the product is not a pain reliever and does not have a direct analgesic effect.

Yes. Actolind Gel Plus can be used for the care of open wounds following amputation. After amputation, keeping the wound surface clean, controlling biofilm formation, and maintaining an appropriate moisture balance are important for the healing process. Actolind Gel Plus supports wound care, helps create an appropriate environment for the development of granulation tissue, and supports control of the microbial load that may develop with regular use. Its use should be planned in accordance with the recommendations of the surgeon or wound care team.